ncRNA name | rno-miR-365 |
ncRNA Category | miRNA |
Disease name | diabetic retinopathy (DR) |
Species | Rattus norvegicus |
Tissues/Cell_line | rat Müller cell line rMC-1; retinas |
Methods | qRT-PCR, luciferase report assay, Western blot, immunofluorescence, in situ hybridization (ISH), ERG |
Expression pattern | up-regulated |
Functional description | miR-365 was found to be highly expressed in the retina and the abnormality of miR-365/Timp3 pathway is closely related to the pathology, like Müller gliosis, and the visual injury in DR. |
PubMed ID | 29196060 |
Year | 2018 |
Title | miR-365 promotes diabetic retinopathy through inhibiting Timp3 and increasing oxidative stress. |
Drug-related ncRNA | NO |
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